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[51] isolated bronchial tissue from patients with and without COPD, isolated and cultured goblet cells and promoted their differentiation and found that SAM-pointed domain-containing ETS transcription factor (SPDEF) and forkhead box protein A2 (FOXA2) had abnormal DNA methylation during goblet cell differentiation

Air purifiers can significantly reduce the presence of cigarette smoke in the air, but they may not completely eliminate it

That doesnt mean nuance should be entirely absent from the conversation